Researchers from the Miami University in Ohio have optimized a new technique that will allow scientists to evaluate how potential inhibitors work on antibiotic-resistant bacteria. This technique, called native state mass spectrometry, provides a quick way for scientists to identify the best candidates for effective clinical drugs, particularly in cases where bacteria can no longer be treated with antibiotics alone.
Historically, shared resources have often been managed with an aim toward averting "tragedies of the commons," which are thought to result from selfish overuse. Writing in BioScience (https://academic.oup.com/bioscience/article-lookup/doi/10.1093/biosci/biab052), Drs. Senay Yitbarek, Karen Bailey, Nyeema Harris, and colleagues critique this model, arguing that, all too often, such conservation has failed to acknowledge the complex socioecological interactions that undergird the health of resource pools.
Mathematicians created a novel mathematical model and found that a mixture of repayment strategies might be best--depending on how much is borrowed and how much income the borrower has.
To boost employees' creativity, managers should consider offering a set of rewards for them to choose from, according to a new study by management experts at Rice University, Tulane University, the University of North Carolina at Greensboro and National Taiwan Normal University.
Smartphone apps have proved invaluable for helping people manage chronic pain during the COVID-19 pandemic, but researchers warn that the need for information sharing and education in this area is being neglected.
For "deep" products, properly managing customers' onboarding experience and using the right channel and right product promotional strategy can enhance long-term customer loyalty and increase sales and profitability.
MIAMI--In a new analysis on managed retreat--the climate adaptation response of moving people and property out of harm's way--researchers explore what it would take for managed retreat to be supportive of people and their priorities. A key starting point is considering retreat alongside other responses like coastal armoring and not just as an option of last resort.
The Scientists Advocate Shifting the Current Value System, which is Biased Against Women and Minorities, Towards a More Diverse and Inclusive Model of Science
By cleverly combining complementary sequencing techniques, researchers of Ghent University, together with Baylor College of Medicine and the world's leading sequencing company, Illumina, have deepened our understanding of the function of known RNA molecules and discovered thousands of new RNAs. A better understanding of our transcriptome is essential to better understand disease processes and uncover novel genes that may serve as therapeutic targets or biomarkers.
While stents are highly effective, scarring or clotting of unhealed stents can occur and lead to complications. Approaches to understand stent healing based on their biological clotting status is unavailable in patients. To devise a potential solution, Dr. Jason McCarthy, an Associate Professor at MMRI, and his team developed a fluorescent probe that binds to activated platelets, allowing the potential for clinicians to proactively treat patients before the development of occlusive stent clotting or scarring.