A modified form of poliovirus, pioneered at Duke Cancer Institute as a therapy for glioblastoma brain tumors, appears in laboratory studies to also have applicability for pediatric brain tumors when used as part of a cancer vaccine.
Over the next 100 years, more than 74 million cervical cancer cases and 60 million deaths could be averted, and the disease eliminated in the 78 countries with the highest disease burden, according to two modelling studies published in The Lancet.
The mechanism behind how HIV can develop resistance to a widely-prescribed group of drugs has been uncovered by new research from the Crick and Dana-Farber Cancer Institute, with the findings opening the door to the development of more effective treatments.
Over the past year, at least seven children have died from diseases including influenza while being detained by the US Department of Homeland Security's Customs and Border Protection (CBP) agency. Infectious disease experts at the University of Maryland School of Medicine (UMSOM) called for protections like influenza vaccinations to prevent serious outbreaks.
A new analysis, published in The Lancet, includes 99 patients with laboratory-confirmed 2019 novel coronavirus (2019-nCoV) who were transferred to Jinyintan Hospital, an adult infectious disease hospital admitting the first 2019-nCoV cases from hospitals across Wuhan, between January 1 and January 20, 2020. The study includes the first 41 cases from Wuhan reported in The Lancet last week .
A new genetic analysis of 10 genome sequences of novel coronavirus (2019-nCoV) from nine patients in Wuhan finds that the virus is most closely related to two bat-derived SARS-like coronaviruses, according to a study published in The Lancet.
First identified in 2012, the MERS-coronavirus is capable of causing severe pneumonia. There are no effective treatments for MERS. Researchers from the German Center for Infection Research (DZIF) at Charité - Universitätsmedizin Berlin identified a cellular recycling process known as autophagy as a potential target in the fight against MERS. Autophagy-inducing substances - including licensed drugs - were shown to be capable of reducing the viral replication rate (Nature Communications).
This week in mSphere, an international group of researchers describe how to use enrichment -- one such emerging NGS strategy -- for monitoring coronaviruses, especially those that originate in bats.
Few studies have identified the effects of zika virus infection on astrocytes, as well as their association with developmental alterations, including brain malformations and microcephaly. Published in Scientific Reports, a new article sought to unravel the virus reactions on laboratory-created astrocytes, comparing them to the same cells present in the brain tissue of animals and fetuses infected with Zika.
Arlington, Va. - New research funded by the Frozen Food Foundation evaluates current environmental monitoring practices being implemented across the frozen food industry to prevent and control Listeria monocytogenes (Lm). The findings were published in the Jan. 24, 2020, Journal of Food Protection®.