Researchers highlight the anti-inflammatory response taking place after birth and designed to shield the newborn from infection. Early protection is ensured by the innate immunity through the rapid development of the complement pathway during the first week after birth.
New research from Edith Cowan University (ECU) has revealed that training one arm can improve strength and decrease muscle loss in the other arm - without even moving it. The findings could help to address the muscle wastage and loss of strength often experienced in an immobilised arm, such as after injury, by using eccentric exercise on the opposing arm.
Virologists at Institut national de la recherche scientifique (INRS) have identified a critical role played by a cellular protein in the progression of Hepatitis C virus infection, paving the way for more effective treatment. No vaccine currently exists for Hepatitis C virus infection, which affects more than 130 million people worldwide and nearly 250,000 Canadians. Antivirals exist but are expensive and not readily available in developing countries, where the disease is most prevalent.
The findings redefine how the so-called gut microbiome operates and how our bodies coexist with some of the 100 trillion bacteria that make it up. The discoveries could lead to new therapies for inflammatory bowel disease and people who've had portions of their bowels removed due to conditions like colon cancer and ulcerative colitis. They also help explain why the use of antibiotics can create a multitude of problems in the digestive system.
A new and improved cat genome developed by the feline research teams at the University of Missouri and Texas A&M University has already proven to be a valuable tool for feline biomedical research by helping to confirm existing gene variants and new candidate genes underlying diseases in cats. The new findings are published October 22nd in PLOS Genetics.
A low dose of ketamine, administered intravenously, does not alter a healthy human's tolerance to blood loss. In other words, if someone was given ketamine to kill pain associated with a battlefield injury, they would be able to tolerate blood loss just as well as someone who did not received this pain killer.
Materials science researchers at the University of California, Irvine conducted a nanoscopic examination of the diabolical ironclad beetle, a species native to the Southwestern US, to learn what makes it so tough and crush resistant. Their results are the subject of a new study in Nature.
Converting heat into electricity is a property thought to be reserved only for stiff materials like crystals. However, researchers--inspired by the infrared (IR) vision of snakes--developed a mathematical model for converting soft, organic structures into so-called 'pyroelectric' materials. The study, appearing October 21, 2020 in the journal Matter, proves that soft matter can be transformed into a pyroelectric material and potentially solves a long-held mystery surrounding the mechanism of IR vision in snakes.
Researchers from the University of Tsukuba identified a novel mechanism by which mating affects the behavior of germline stem cells (GSCs). By studying Drosophila melanogaster, the researchers showed that the neurons that are activated during mating result in increased intracellular calcium signaling in cells adjacent to GSCs, which in turn resulted in the activation of the protein matrix metalloproteinase to increase GSCs. This study describes how stem cell behavior is regulated by environmental cues.
A preclinical study led by University of South Florida Health neuroscientists indicates that an antigen-presenting dendritic vaccine with a specific antibody response to oligomeric Aβ may be safer and offer clinical benefit in treating Alzheimer's disease. The vaccine uses immune cells known as dendritic cells loaded with a modified Aβ peptide as the antigen.