A new study has identified the master regulator that maintains a healthy gut and limits damage by parasitic whipworms. Researchers from the Wellcome Sanger Institute and collaborators revealed the interleukin 10 receptor (IL-10R) is critical to prevent uncontrolled whipworm infection in mice and a damaging immune response in the gut. The study, published today in PLOS Pathogens, helps understand the signalling mechanism that maintains a balance between the host, whipworms and gut bacteria.
Disrupting two genes involved in the preservation of RNA molecules inhibits the ability of the male form of the malaria parasite to mature and be transmitted from human blood into mosquitoes, interrupting a key stage in the parasite's life-cycle and cutting off an important step in the spread of the disease.
University of South Florida-led research identifies individual hosts more or less likely to escalate outbreaks.
Researchers at the University of Sydney have found that the relationship between the Varroa mite and virulence of a virus of honey bees, has been misunderstood. The study challenges the long-held belief that the parasitic Varroa mite transmits the deformed wing virus of honeybees and in doing so changes the virus to make it more virulent and deadly. Research published today concludes that this belief is incorrect.
Sequencing gut microbiomes typically turns up new microbes and other denizens of the intestinal tract, including viruses or phages that prey on these microbes. A new UC Berkeley study has discovered the largest phages every found in humans, with genomes 10 times the average and larger than the genomes of the smallest bacteria. They target bacteria found primarily in people eating non-Western diets. Their large size blurs the line between life and non-life.
After major global successes in the battle against malaria, the positive trend stalled around 2015 -- apart from in Zanzibar in East Africa, where only a fraction of the disease remains. In a new study published in BMC Medicine, researchers at Karolinska Institutet in Sweden explain why this was and show that new strategies are needed to eradicate the disease. One of the problems is a change in mosquito behaviour and selection in the parasites.
A type of mosquito that transmits malaria has been detected in Ethiopia for the first time, and the discovery has implications for putting more people at risk for malaria in new regions, according to a study led by a Baylor University researcher.
Ozaena ground beetles likely have anatomical adaptations enabling them to parasitize ant nests throughout their life cycle, according to a study published Jan. 16, 2019, in the open-access journal PLOS ONE by Wendy Moore from the University of Arizona, USA, and colleagues.
The cyanobacteria blooms that plague western Lake Erie each summer are both an unsightly nuisance and a potential public health hazard, producing liver toxins that can be harmful to humans and their pets.
Among the many threats to honey bee colonies around the world, one stands alone: the parasitic mite, Varroa destructor. For decades, researchers assumed that varroa mites feed on blood, like many of their mite and tick cousins. But new University of Maryland-led research suggests that varroa mites have a voracious appetite for a honey bee organ called the fat body, which serves many of the same vital functions carried out by the human liver.