Shuffling of DNA in a single gene might be why the syphilis bacteria can evade the immune system. The change alters a protein on its cell surface to create a distraction. People can become re-infected several times with syphilis because they can't develop immunity, Untreated syphilis can hide in the body for decades. Genomic findings on these evasive strategies may point to designs for vaccines to outwit syphilis' defenses.
Experts from UNC Chapel Hill review possible clinical approaches from antivirals to gene therapy against the virus responsible for COVID-19 and related diseases.
A new approach to monitoring the novel coronavirus, (as well as other dangerous pathogens and chemical agents), is being developed and refined. Known as wastewater-based epidemiology (WBE), the method mines sewage samples for vital clues about human health. It can potentially identify levels of coronavirus infection at both a local and global scale.
Have you ever noticed how a bite of warm cherry pie fills your mouth with sweetness, but that same slice right out of the refrigerator isn't nearly as tempting? Scientists know this phenomenon to be true, but the mechanism behind it has been poorly understood.
When iron is limited, the microalgae that live within coral cells change how they take in other trace metals, which could have cascading effects on vital biological functions and perhaps exacerbate the effects of climate change on corals.
UC San Francisco virologist Raul Andino, PhD and Andrew Macadam, PhD, of the UK's National Institute for Biological Standards and Control (NIBSC) report promising Phase 1 clinical results for the first new oral polio vaccine in 50 years, which they have designed to be incapable of evolving the ability to cause disease in humans.
Despite the importance of sweet potato, little is known about the sweet potato microbiome. ;A plant's microbiome profoundly impacts its health and development,' explains Brooke Bissinger, an entomologist who recently published a study on sweet potatoes in Phytobiomes Journal. 'We sought to better understand the sweet potato microbiomes by characterizing it within and between actual working farms.'
The common view of heredity is that all information passed down from one generation to the next is stored in an organism's DNA. But Antony Jose of the University of Maryland, disagrees. In two new papers, Jose argues DNA is just the ingredient list, not the set of instructions used to build and maintain a living organism. The instructions, he says, are stored in the molecules that regulate a cell's DNA and other functioning systems.
In a study that could lead to a new vaccine against malaria, researchers have found antibodies that trigger a 'kill switch' in malarial cells, causing them to self-destruct.
Would you like to be able to find out which antibiotic combination works best for a particular patient? And do it in just 12 or maybe even six hours, in a point-of-care? Or maybe search for antibodies in thousands of samples at a time? It's all possible with a new device invented by scientists from IPC PAS. It is cheap, fast & reliable, it can replace strip tests and give patients a better chance to fight disease.