An international team of life scientists has identified a key gene in the transmission of African sleeping sickness -- a severe disease transmitted by the bite of an infected, blood-sucking tsetse fly, which is common in Sub-Saharan Africa. The disease is fatal if untreated. Tens of millions of people in 36 countries are at risk. There is no vaccine, and conventional drug treatments are not very effective and have severe side effects.
The global burden of COPD is high, and prevalence of nonsmokers with COPD has been increasing. In a study to be presented at CHEST Congress Thailand 2019, researchers in Nagpur, India, sought to describe the characteristics of nonsmoking patients with COPD and to determine associated comorbidities and exposures.
Food insecurity -- that is, limited access to sufficient safe and nutritious food at home -- negatively impacts on the learning ability of adolescents in India, new research shows.
In a new report, titled 'Access Barriers to Antibiotics' (available April 11, 2019) researchers at the Center for Disease Dynamics, Economics & Policy conducted stakeholder interviews in Uganda, India, and Germany, and literature reviews to identify key access barriers to antibiotics in low-, middle-, and high-income countries. The report makes several recommendations proposing action on R&D, strengthening regulatory capacities, encouraging the development and diversification of quality local manufacturing, exploring innovative funding to reduce out-of-pocket payments, better treatment guidelines, and awareness raising.
An analysis led by ISGlobal, an institution supported by 'la Caixa,' identifies African regions where ivermectin administration to livestock would have the greatest impact on malaria transmission. The results, published in Scientific Reports, point to West Africa, below the Sahel, where malaria prevalence is very high.
Scientists have created a molecule with both strong anti-Zika properties and low toxicity to animal cells.
Opitz C syndrome (OCS), an ultra-rare disease that causes serious physical and intellectual disabilities, has an heterogeneous genetic base that makes its medical diagnostic and therapeutic intervention difficult. A new study concludes that this severe and extremely rare disease could be considered a 'private syndrome' for each patient.
Mass drug administration of two antibiotics can be highly effective at reducing cases of scabies and the bacterial infection impetigo, according to new research published in Lancet Infectious Diseases.
Researchers have turned a fungus into a disease-curing factory through modern genetic engineering and patience. The natural antibiotic is a promising cure for a neglected tropical disease called human African trypanosomiasis, or African sleeping sickness, that infects thousands of people in remote, rural areas of sub-Saharan Africa each year.
Public health officials could soon be able to detect viruses in mosquitoes in the wild much more quickly and easily -- thanks to the insect equivalent of a urine test. A new study in Australia shows that two kinds of commonly used mosquito traps can be readily modified to collect mosquito excreta, or liquid waste droplets, to be tested for signs of viruses.