The Chemical Checker provides processed, harmonized and ready-to-use bioactivity information on more than 1M small molecules. The tool, developed by the Structural Bioinformatics and Network Biology lab at IRB Barcelona, has been published in Nature Biotechnology.
WSU scientists present a new model that allows winemakers to get measurements in their wine that previously required difficult, tedious, or expensive testing.
An international team of researchers has developed a reliable method for assessing the role of such RNAs. The new technique and the data obtained with it allow generating important hypotheses on how chromatin is composed and regulated, as well as identifying the specific functions of lncRNAs.
The genomes of three carnivorous plants -- the Venus flytrap, spoon-leaved sundew and the waterwheel plant -- have been decoded. The result has caused some surprises.
Scientists analyzed the genomes of extinct and living lions. They managed to determine when the divergence took place, as well as come to several other conclusions on genetic diversity of the modern lion population in India.
Science has published in its latest issue two papers by Associate Professor Emma Schymanski, whose team develops methods to identify unknown chemicals and their effects on health and disease.
A hallmark of cancer cells is that they lack contact inhibition, even when crowded. A new study from Scripps Research reveals a protein biologists thought they knew well, YAP, is playing an unexpected role in switching off that normal response, with input from many players.
Duality Technologies Researchers Accelerate Privacy-Enhanced Collaboration on Genomic Data - with Significant Implications for COVID-19 Research. In a paper published in PNAS, a research team of data scientists and cryptographers detail accurate privacy-enhanced Genome-Wide Association Studies (GWAS) of over 25,000 individuals using Homomorphic Encryption to yield results 30 times faster than prior secure computation methods. GWAS is crucial in understanding complex diseases.
For something that has evolved with us over millions of years, and remains part of our physiology over our entire lives, our gut microbiome, oddly, remains somewhat of a mystery. Comprised of trillions of microbes of at least a thousand different species, this community of bacteria, viruses, protozoa and fungi in our gastrointestinal tracts is unique to each individual and has been found to be intimately connected to various fundamental aspects of our fitness, from our immunity to our metabolism and mental health.
Researchers from the Hubrecht Institute and Utrecht University generated an in-depth description of the human hormone-producing cells of the gut. These cells are difficult to study, as they are very rare and unique to different species of animals. The researchers developed tools to study human hormone-producing cells in mini-guts grown in the lab, called organoids. Their findings offer potential new avenues for the treatment of diseases such as type 2 diabetes and obesity.