New findings about critical cellular structures have upended common assumptions about their formation and composition and provided new insight how molecular machines are built in living cells.
A microbial community is a complex, dynamic system composed of hundreds of species and their interactions, they are found in oceans, soil, animal guts and plant roots. Each system feeds the Earth's ecosystem and their own growth, as they each have their own metabolism that underpin biogeochemical cycles. Researchers from the School of Life Sciences at the University of Warwick have produced an extendable thermodynamic model for simulating the dynamics of microbial communities.
The lab of Xavier Saelens (VIB-UGent Center for Medical Biotechnology) announces the isolation and characterization of a unique antibody that can bind to the virus that causes COVID-19 (SARS-CoV-2). The antibody was described in collaboration with research groups in the US. The team has established that the antibody binds to a conserved epitope on the spike protein of SARS-CoV-2.
Researchers at Singapore-MIT Alliance for Research and Technology (SMART), Wuhan University, Shanghai Jiao Tong University, and Tsinghua University have discovered a previously unknown anti-phage defence mechanism in some bacteria that uses unique new ways to protect itself against phages. The discovery explains why some bacteria are resistant to phage therapy, and can pave the way to overcome existing challenges in fighting bacteria using phage therapy.
In 2012, the European Union MetaCardis consortium (www.MetaCardis.net), comprising 14 research groups from six European countries with multidisciplinary expertise set out to investigate a potential role of the gut microbiota in the development of cardio-metabolic diseases. This project, coordinated by Prof Karine Clément at INSERM (France) studies more than 2,000 deeply phenotyped European participants in health and at different stages of cardiometabolic disease (obesity, diabetes and cardiovascular diseases).
A study just released by Columbia University Mailman School of Public Health is reporting a blood-DNA-methylation measure that is sensitive to variation in the pace of biological aging among individuals born the same year. The tool - DunedinPoAm -- offers a unique measurement for intervention trials and natural experiment studies investigating how the rate of aging may be changed by behavioral or drug therapy, or by changes to the environment.
A University of Houston biomedical researcher has discovered a difference in urinary biomarker proteins of lupus nephritis in patients according to race. The findings have implications for early diagnosis and new treatments.
Researchers from NUS and the University of Tokyo have developed a new device that can monitor bladder volume in real-time and effectively empty the bladder.
Electrochemical reactions include the transformation of sugars into alcohol and carbon dioxide, and similar processes occur when the body breaks down food, drugs or other compounds. Monitoring these metabolic processes helps in testing, studying and combating disease, but they are difficult to study with normal equipment. In this week's Review of Scientific Instruments, researchers discuss their work with a miniaturized potentiostat, which is compatible with most 3-electrode biosensors and can transmit its measurements via Bluetooth.
When we fall asleep, our brains are not merely offline, they're busy organizing new memories -- and now, scientists have gotten a glimpse of the process. Researchers report in the journal Cell Reports on May 5, 2020, the first direct evidence that human brains replay waking experiences while asleep, seen in the brains of two participants who had been implanted with microelectrode arrays as part of a brain-computer interface pilot clinical trial.