Using CRISPR gene editing, researchers have thwarted a lethal lung disease in an animal model in which a harmful mutation causes death within hours after birth. This proof-of-concept study showed that in utero editing could be a promising new approach for treating lung diseases before birth.
In a paper recently published in the journal Biological Conservation, an international team of conservationists highlights the importance of tree dens as a choice for pandas raising infants in native habitats. The study, conducted in Fengtongzai Reserve in China, analyzed the difference in microhabitats of cave dens and tree dens used by female pandas. The result of the research suggests that conservation efforts need to take into account species use of microhabitats and habitat features as well as overall ecological systems.
Why do some animals eat or abandon their offspring? According to researchers at the University of Tennessee and the University of Oxford, these might actually be forms of parental care. Published in Frontiers in Ecology and Evolution, their mathematical model shows that when overcrowding threatens offspring survival -- which often occurs due to spread of infection or competition for resources -- sacrificing a few so the most can live becomes the ultimate form of tough love.
Offering universal late pregnancy ultrasounds at 36 weeks would benefit mothers and babies and could be cost saving. A new study shows that an additional routine ultrasound could eliminate undiagnosed breech presentation of babies, lower the rate of emergency caesarean sections, and improve the health of mothers and babies.
Transitioning transgender adolescents are forced to consider whether or not they pursue fertility preservation. Their decision is influenced by certain key factors, reports a new study.
A number of plant and animal species could find it increasingly difficult to reproduce if climate change worsens and global temperatures become more extreme -- a stark warning highlighted by new scientific research.
An animal's choice of mating partner can be influenced by what it eats during its sexual development, a study of insects has shown.
Cell-by-cell genetic analyses of developing brain tissues in neonatal mice and laboratory models of brain cancer allowed scientists to discover a molecular driver of the highly aggressive, deadly, and treatment-resistant brain cancer, glioblastoma. Published in Cell Stem Cell, the findings present an opportunity to find out if new therapeutic approaches can stop glioblastoma at its earliest stages of initial formation or recurrence.
When mitochondria become damaged, they avoid causing further problems by signaling cellular proteins to degrade them. In a paper publishing April 11, in the journal Developmental Cell, scientists in Norway report that they have discovered how the cells trigger this process, which is called mitophagy. In cells with broken mitochondria, two proteins -- NIPSNAP 1 and NIPSNAP 2 -- accumulate on the mitochondrial surface, functioning as 'eat me' signals, recruiting the cellular machinery that will destroy them.
St. Jude Children's Research Hospital scientists have cracked the mystery surrounding the most common genetic cause of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease. The research suggests possible new approaches to diagnosis and treatment of the lethal disorder.