Genes are like instructions, but with options for building more than one thing. Daniel Larson, senior investigator at the National Cancer Institute, studies this gene 'splicing' process, which happens in normal cells and goes awry in blood cancers like leukemia.
Sleep-deprived fruit flies helped reveal what induces sleep. University of Oxford researchers Anissa Kempf, Gero Miesenböck, and colleagues reveal that fruit fly sleep is driven by oxidative stress, the imbalance of free radicals and antioxidants in the body.
More than half of all cancer patients undergo radiation therapy and the dose is critical. Too much and the surrounding tissue gets damaged, too little and the cancer cells survive.
The top contributor to familial Parkinson's disease is mutations in leucine-rich repeat kinase 2 (LRRK2), whose large and difficult structure has finally been solved, paving the way for targeted therapies.
The piece of gold that Richard Taylor was thrilled to track down weighed less than a single bacterium. Taylor, a postdoctoral fellow at the Max Planck Institute, was working to follow individual nanogold-labeled molecules that move just nanometers, billionths of a meter.
Even though they don't have conventional noses, insects have adapted to smell odors in nearly every imaginable niche. Mosquitoes find us by our odor molecules binding to odor receptors on their antennae, bees are drawn to flowers the same way, whereas ticks detect an approaching host using receptors on their forelegs.
Yvonne Chen engineers immune cells to target their most evasive enemy: cancer. New cancer immunotherapies generate immune cells that are effective killers of blood cancers, but they have a hard time with solid tumors.
Accountable Care Organizations -- or ACOs -- formed for the first time in 2011, designed to combat rising medical costs and provide more coordinated care to Medicare patients. But the savings have been inconsistent nationwide. A new Portland State University study looked at what's driving those inconsistencies and what ACOs might do to resolve the issue.
A new report from the National Academies of Sciences, Engineering, and Medicine has found that citizen science is reshaping research. It can greatly facilitate large-scale research by providing opportunities to study more topics while teaching people more about science and enhancing science education. The report is one of the first of its kind to examine the available information on citizen science projects and, through peer-reviewed evidence, clearly identify trends, weaknesses and opportunities for growth.
Researchers at Texas Heart Institute and UCLA crossed a major milestone in the development of a wirelessly powered, leadless pacemaker and further advanced the possibility of using wirelessly powered, biventricular pacing to address cardiac resynchronization challenges. In Nature Research Scientific Reports, they reported the first proof of the novel pacing system's ability to provide synchronized biventricular pacing in a closed chest and open chest, preclinical research model.