The results of a clinical trial released today in STEM CELLS Translational Medicine demonstrate how a topical solution made up of stem cells leads to the regrowth of hair for people with a common type of baldness.
A Duke University research team has found a small area of the brain in mice that can profoundly control the animals' sense of pain. Somewhat unexpectedly, this brain center turns pain off, not on. It's located in an area where few people would have thought to look for an anti-pain center, the amygdala, which is often considered the home of negative emotions and responses, like the fight or flight response and general anxiety.
It's not just the presence of bacteria that can lead to disease; their spatial arrangement also matters. When University of Pennsylvania and Georgia Tech scientists examined the bacteria that causes tooth decay, they found it 'shields' itself under blankets of sugars and other bacteria in a crown-like arrangement, helping it evade antimicrobials and concentrate its tooth-damaging acids.
Researchers from Sechenov University (Russia) and University of Pittsburgh (USA) discovered that the resistance of innate immune cells, macrophages, to ferroptosis -- a type of programmed cell death -- depends on the type of their activation. It turned out that cells helping tissues to recover from inflammation were more vulnerable. The researchers identified the mechanisms underlying the cells' resistance and explained how this research would help regulate inflammation in a paper published in Nature Chemical Biology.
The study now published in Nature Cell Biology reveals more information on the capacity of plants, identified as 'epigenetic memory,' which allows recording important information to, for example, remember prolonged cold in the winter to ensure they flower at the right time during the spring.
Photopharmacology investigates the use of light to switch the effect of drugs on and off. Now, for the first time, scientific teams from Jena, Munich, and New York have succeeded in using this method to control a component of cells that was previously considered inaccessible.
UC Riverside scientists have solved a 20-year-old genetics puzzle that could result in ways to protect wheat, barley, and other crops from a devastating infection.
Research from the University of Sheffield has given new insight into the cause of mutations in pluripotent stem cells and potential ways of stopping these mutations from occurring.
A team of biochemists and virologists at Goethe University and the Frankfurt University Hospital were able to observe how human cells change upon infection with SARS-CoV-2, the virus causing COVID-19 in people. The scientists tested a series of compounds in laboratory models and found some which slowed down or stopped virus reproduction. These results now enable the search for an active substance to be narrowed down to a small number of already approved drugs.
Scientists have discovered a new treatment to dramatically reduce swelling after brain and spinal cord injuries, offering hope to 75 million victims worldwide each year.