In their study, published in Cell, the researchers demonstrated that specific groups of neurons, known as neuronal ensembles, have a causal role in behavior. The researchers used new optical and analytical tools to identify cortical ensembles in mice while they performed a visual task. They also used high-resolution optogenetics to simultaneously target selected neurons with single-cell precision, taking control of the mice's behavior.
A study with 2,147 children explored the association between prenatal exposure to methylmercury, intellectual coefficient at 8 years of age, and genotype
Data for 154,089 older men diagnosed with prostate cancer were used to analyze the association between androgen deprivation therapy, a hormone-suppressing therapy used to treat prostate cancer, and subsequent diagnosis of Alzheimer disease or dementia. Of the men, 62,330 (average age 76) received androgen deprivation therapy within two years of being diagnosed with prostate cancer and 91,759 men (average age 74) didn't have such treatment.
In a Psycho-Oncology study of patients newly diagnosed with lymphoma or multiple myeloma, one-third of participants reported depressive symptoms around the time of diagnosis, and depressive symptoms were linked with shorter survival.
Depression is common in people with inflammatory bowel disease (IBD), but the actual causes of depression in this group are unknown. In a Neurogastroenterology & Motility study, depression was linked with more severe IBD symptoms, and a less positive cognitive bias in emotional recognition (a reduced ability to recognize basic emotions in others) was involved in this association.
In a Cancer Medicine study of 298,434 patients diagnosed with breast cancer between 2004 and 2012, married patients had a better prognosis than patients who were single, who in turn had a better prognosis than those who were divorced, separated, or widowed.
Treatment for psychosis can be targeted to a specific structural mutation, according to a new study published by researchers from McLean Hospital.
Military veterans exposed to combat were more likely to exhibit signs of depression and anxiety in later life than veterans who had not seen combat, a new study from Oregon State University shows.
Antidepressants reduce deaths by more than a third in patients with diabetes and depression, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.
UAB researchers say over expression of NEAT1, an noncoding RNA, appears to diminish the ability of older brains to form memories. Inhibiting NEAT1 via CRISPR technology could be a means to improve memory in older humans.