Researchers from North Carolina State University have developed an artificial enzymatic pathway for synthesizing isoprenoids, or terpenes, in E.coli. This shorter, more efficient, cost-effective and customizable pathway transforms E. coli into a factory that can produce terpenes for use in everything from cancer drugs to biofuels.
Smoking has long been proven to negatively affect people's overall health in multiple ways. The study shows that the smokers demonstrated a higher aging ratio, and both male and female smokers were predicted to be twice as old as their chronological age as compared to nonsmokers.
intentionally controlled light can help regulate human health and productivity by eliciting various hormonal responses. Tailored LED wavelengths and intensities also can efficiently stimulate plant growth, alter their shapes and increase their nutritional value, opening a new world of scientific and technological possibilities for indoor farming.
Scientists have long employed relatively simple guidelines to help explain the physical world, from Newton's second law of motion to the laws of thermodynamics. Biomedical engineers at Duke University have used dynamic modeling and machine learning to construct similarly simple rules for complex biology. They have devised a framework to accurately interpret and predict the behavior of mutually beneficial biological systems, such as human gut bacteria, plants and pollinators, or algae and corals.
Schizophrenia could be caused by a genetic mutation that causes a structural abnormality in the brain during adolescence. Therefore testing for the gene SLC39A8, and brain scans for schizophrenia could predict whether or not someone will develop it -- researchers at the University of Warwick have found.
New study uses live imaging to understand a critical step in early embryonic development--how genes and molecules control forces to orchestrate the emergence of form in the developing embryo. The study findings could have important implications for how stem cells are used to create functional organs in the lab, and lead to a better understanding of the underlying causes of gastrointestinal birth defects.
Multiple sclerosis is a demyelinating inflammatory disorder in which autoreactive T cells migrate into the central nervous tissue and damage oligodendrocytes and myelin, which protect nerve cells. Sephin1 prolongs a cytoprotective response in oligodendrocytes, protecting those cells and myelin from this inflammatory attack. It dampens central nervous system inflammation, limits myelin damage and reduces the reactivation of T cells
Anxiety and depression in young children are hard to detect and often go untreated, potentially leading to anxiety disorders and increased risk of suicide and drug abuse later. In a PLOS ONE study, researchers showed a wearable sensor detected these 'internalizing disorders' in children with 81 percent accuracy, reducing to 20 seconds what would take clinicians months to diagnose, opening the door to inexpensive screening that could be part of routine developmental assessments.
Using a novel patient-specific stem cell-based therapy, researchers at the National Eye Institute (NEI) prevented blindness in animal models of geographic atrophy, the advanced 'dry' form of age-related macular degeneration (AMD), which is a leading cause of vision loss among people age 65 and older. The protocols established by the animal study set the stage for a first-in-human clinical trial testing the therapy in people with geographic atrophy, for which there is currently no treatment.
University of Montana Professor Diana Six is one of 12 authors of a new report that addresses the potential for biotechnology to provide solutions for protecting forest trees from insect and pathogen outbreaks, which are increasing because of climate change and expanded global trade.