For white patients, lipid test results showing high HDL cholesterol and low LDL cholesterol and triglycerides would be good news, suggesting a lower risk for heart disease. However, African Americans have more severe heart disease despite having high HDL and low triglycerides. Medical University of South Carolina researchers report in PLOS ONE that changes in sphingolipid levels correlate with a higher risk of heart disease in African American patients with lupus.
- PLOS ONE
- National Center for Advancing Translational Sciences, South Carolina Clinical & Translational Research Institute), National Institutes of Health, MUSC Multidisciplinary Clinical Research Center; Lipidomics Shared Resource