New analysis examines light scattering properties in brain tissue to better understand the three-dimensional structure of nerve fibers.
Researchers invented a microfluidic chip containing cardiac cells that is capable of mimicking hypoxic conditions following a heart attack - specifically when an artery is blocked in the heart and then unblocked after treatment. The chip can be used to monitor electrophysiological and molecular response of the cells to heart attack conditions in real time.
A joint research team of POSTECH, The Catholic University, and City University of Hong Kong developed an 'in vivo priming' with heart-derived bioink. Using engineered stem cells and 3D bioprinting technology, they began developing medicines for cardiovascular diseases.
A new technique allows researchers to test how the deformation of tiny train track-like cell proteins affects their function. The findings could help clarify the roles of deformed 'microtubules' in traumatic brain injuries and in neurological diseases like Parkinson's.
The interaction between biotin and streptavidin is a well-established experimental tool in bionanotechnology. Ludwig-Maximilians-Universität (LMU) in Munich physicists have now shown that the mechanical stability of the complex is dependent on the precise geometry of the interface.
The increase in the CO2 concentration of the atmosphere does not compensate the negative effect of greenhouse gas-induced climate change on trees: The more extreme drought and heat become, the less do trees profit from the increased supply with carbon dioxide in terms of carbon metabolism and water use efficiency. This finding was obtained by researchers of Karlsruhe Institute of Technology (KIT) when studying Aleppo pines. Their study is reported in New Phytologist (DOI: 10.1111/nph.16471).
Scientists create model to measure how cells sense their surroundings.
In a recent study published in Autophagy, researchers at Kanazawa University show how abnormalities in a gene called TPR can lead to pediatric brain cancer.
A transport protein that is used by the human pathogen Mycobacterium tuberculosis to import vitamin B12 turns out to be very different from other transport proteins. It contains a huge water-filled cavity, in which hydrophilic substances are transported across the cell membrane. This discovery, which changes our understanding of bacterial physiology, was made by imaging the transport protein using cryo-electron microscopy. The results were published in the journal Nature on 26 March.
Researchers have developed the first computational model of a human cell and simulated its behavior for 15 minutes -- the longest time achieved for a biological system of this complexity. In a new study, simulations reveal the effects of spatial organization within cells on some of the genetic processes that control the regulation and development of human traits and some human diseases.