In advance of a widely-watched national referendum vote to be held this September, two drug policy experts from Massey University have identified gaps and challenges in New Zealand's proposal for legalizing recreational cannabis.
Researchers used single-nucleus RNA sequencing to compare transcriptional responses to acute cocaine in 16 unique cell populations from the brain nucleus accumbens. The atlas is part of a major study that used multiple cutting-edge technologies to describe a dopamine-induced gene expression signature that regulates the brain's response to cocaine. The study shows neurobiological processes that control drug-related adaptations and reveals new information about how transcriptional mechanisms regulate activity-dependent processes within the central nervous system.
Cannabis use can lead to behavioral changes, including reduced social interactions in some individuals. To better understand the phenomenon, Inserm researcher Giovanni Marsicano and his team from NeuroCenter Magendie (Inserm/Université de Bordeaux), in collaboration with Juan Bolaños' team from the University of Salamanca, have identified for the first time in mice the cerebral mechanisms underlying the relationship between cannabis and reduced sociability. Their findings have been published in Nature.
A new study from faculty at the Colorado School of Public Health at the University of Colorado Anschutz Medical Campus looks at the relationship between opioid use and driving among older adults. The findings published today in the Journal of the American Board of Family Medicine.
Motherhood takes over the brain's decision-making regions to prioritize caring for offspring, according to new research in rats published in eNeuro.
Center for BrainHealth® recently examined underlying brain networks in long-term cannabis users to identify patterns of brain connectivity when the users crave or have a desire to consume cannabis. While regional brain activation and static connectivity in response to cravings have been studied before, fluctuations in brain network connectivity had not yet been examined in cannabis users. The findings from this study will help support the development of better treatment strategies for cannabis dependence.
As many as 7% of moms-to-be use marijuana while pregnant, and that number is rising fast as more use it to quell morning sickness. But new research suggests such use could have a lasting impact on the fetal brain, influencing children's sleep for as much as a decade.
The opioid and addiction epidemic didn't go away when the coronavirus pandemic began. But rapid changes in regulations and guidance made during COVID-19 response could also help many more people get care for opioid use disorder and other addiction problems, experts say in a new paper. But it will take more changes to truly lower barriers that stand in the way of delivering evidence-based addiction care to more people via telemedicine.
Researchers at the University of Colorado College of Nursing at the Anschutz Medical Campus found that an 18-month pilot project that trained Nurse Practitioners and Physician Assistants to prescribe Medication for Opioid Use Disorders (MOUD) was successful in increasing availability and access of services to residents of two rural Colorado counties experiencing high overdose rates. As a result, the state legislature passed a second bill to expand MOUD into 17 counties.
Researchers looked at whether despair among young adults was associated with suicidal thoughts and behavior and alcohol and drug misuse.