European regulatory expertise centre, the Pharmabiotic Research Institute (PRI), which supports the pharmaceutical development of microbiome-based drug products, a new field of biological medicine, has published a review of the regulatory and scientific requirements needed to properly develop live biotherapeutic products (LBPs). Similarly to other innovative medicinal products, demonstrating the quality, efficacy and safety of these living medicines will require an innovative regulatory and technical approach.
"Citizen scientists" developing homemade COVID-19 vaccines may believe they're inoculating themselves against the ongoing pandemic, but the practice of self-experimentation with do-it-yourself medical innovations is fraught with legal, ethical and public health issues, says a new paper co-written by University of Illinois law professor Jacob S. Sherkow.
The largest ever survey on global public attitudes towards genomic research and data sharing suggests that work is needed to raise levels of public trust in how genetic data is used in order for that data to fulfil its promise to advance human health and medicine.
Research led by ecologists at the University of Toronto examining plastic pollution entering oceans, rivers and lakes around the world annually, outlines potential impacts of various mitigation strategies over the coming decade. The researchers estimate the scale of human response needed to reduce future emissions and manage what's already floating around out there and recommend a fundamental shift to a framework based on recycling where end-of-life plastic products are valued rather than becoming waste.
Despite gender disparities in the workforce, male and female workers in Europe report similar rates of anxiety in response to job insecurity across countries. Economic stress and anxiety can contribute to poor mental health outcomes as more people work non-traditional jobs with little stability, and according to Dr. Egidio Riva, a co-author of the study investigating these trends, such effects need to be taken seriously by both governments and employers alike.
The practice of genome editing - which alters an organism's DNA in ways that could be inherited by subsequent generations - is both more complex and less dramatic than the popular tropes suggest. However, its implications are so profound that a growing group of experts believe it is too important a matter to be left only to scientists, doctors and politicians.
Artificial intelligence researchers have improved the performance of deep neural networks by combining feature normalization and feature attention modules into a single module that they call attentive normalization. The hybrid module improves the accuracy of the system significantly, while using negligible extra computational power.
Using computer modeling, researchers simulated how the distribution of quaking aspen, a native tree known for its brilliant yellow and orange foliage in fall and the sound of its trembling leaves, will change amid rising temperatures over the next 100 years.
A University of Arkansas biologist is part of an international team of researchers is building a volunteer network of citizen scientists to help monitor the abundance of dragonflies and damselflies.
Rising ocean temperatures cause marine heat waves, which place stress on living coral animals, as well as the photosynthetic algae on which they depend for energy. A new study led by Yvonne Sawall, assistant scientist at the Bermuda Institute of Ocean Sciences (BIOS), is showing potential for the use of artificial upwelling (AU)--or the application of cooler, deep water--as a way to mitigate the thermal stress on corals.