Demand for kidney transplants is so high that doctors now routinely accept damaged donor kidneys, with limited means to assess their quality. A new, non-invasive, photoacoustic imaging technique allows doctors to 'see' kidney scarring quickly and accurately with a simple scan. An upcoming, landmark clinical trial will test the new technique on donor kidney quality. The technology could potentially empower doctors to better match donor kidneys to patient life expectancy for longer-lasting transplantation outcomes.
A new study by researchers from McGill University has uncovered that minerals causing aortic heart valve blockage in men and women are different, a discovery that could change how heart disease is diagnosed and treated.
Researchers at Mossakowski Medical Research Center of the Polish Academy of Science have developed a simple method for preparing 3D keratin scaffold models which can be used to study the regeneration of tissue.
A new diagnostic test to quickly and easily monitor kidney transplant patients for infection and rejection relies on a simple urine sample and a powerful partner: the gene-editing technology CRISPR. Michael Kaminski, who developed it, leads a new Emmy Noether Group at the MDC & Charité.
Some insect wings such as cicada and dragonfly possess nanopillar structures that kill bacteria upon contact. However, to date, the precise mechanisms that cause bacterial death have been unknown. Using a range of advanced imaging tools, functional assays and proteomic analyses, a study by the University of Bristol has identified new ways in which nanopillars can damage bacteria.
The European Association for the Study of the Liver (EASL) and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) have issued a Position Paper, providing recommendations for clinicians caring for patients with liver diseases during the current pandemic.
A joint research team of POSTECH, The Catholic University, and City University of Hong Kong developed an 'in vivo priming' with heart-derived bioink. Using engineered stem cells and 3D bioprinting technology, they began developing medicines for cardiovascular diseases.
Researchers at Karolinska Institutet and St Erik Eye Hospital in Sweden have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly. Using the CRISPR/Cas9 gene editing, they have also managed to modify the cells so that they can hide from the immune system to prevent rejection. The studies are published in the scientific journals Nature Communications and Stem Cell Reports.
A stem cell biologist from City University of Hong Kong (CityU), together with his collaborators, has developed a novel strategy, called in vivo priming, to 'train' the stem cells to stay strong after implantation to the damaged heart via the 3D-printed bandage-like patch. The positive results of the study show that an in vivo priming strategy can be an effective means to enhance cardiac repair.
A new study from the University of Birmingham has shown that fecal microbiota rransplants (FMT) are highly successful in treating patients with Clostridioides difficile (C. diff) infection.