Thirty years after scientists first suggested that increased exposure to microorganisms could benefit health, CU Boulder researchers have identified an anti-inflammatory fat in a soil-dwelling bacterium that may be partly responsible. Someday, they hope to use it to develop an immunization against stress-related disorders.
In a paper published recently in the Proceedings of the National Academy of Sciences journal, Dr. Christopher Johnston and his colleagues at the Forsyth Institute describe a new technique to genetically engineer bacteria by making human-made DNA invisible to a bacterium's defenses. In theory, the method can be applied to almost any type of bacteria.
A new compound developed by University of Sheffield experts has killed antibiotic resistant gram-negative bacteria, including E. coli, during tests.
The search for a global Strep A vaccine has narrowed after researchers sequenced the DNA of more than 2,000 Group A Streptococcus samples from around the world. Researchers from the Wellcome Sanger Institute and collaborators revealed the differences between strains from more than 20 countries, and identified potential vaccine targets present in strains from all countries sampled. The study in Nature Genetics points to the possibility of developing an effective global vaccine against Strep A.
Using paper stickers to collect pathogens on surfaces where antisepsis is required, such as in food processing plants, is easier, and less expensive than swabbing, yet similarly sensitive. The research is published in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.
The global spread of antibiotic resistance is a major public health issue and a priority for international microbiology research. In his paper to be published in the journal Science, Christian Lesterlin, Inserm researcher at Lyon's 'Molecular Microbiology and Structural Biochemistry' laboratory (CNRS/Université Claude Bernard Lyon 1), and his team were able to film the process of antibiotic resistance acquisition in real time, discovering a key but unexpected player in its maintenance and spread within bacterial populations.
Leptospirosis is an emerging zoonotic disease that affects more than one million people around the world each year. Researchers reporting in PLOS Neglected Tropical Diseases have now sequenced the genomes of Leptospira collected from environments around the globe and revealed 30 new species and new patterns of species diversity.
Researchers have discovered that humans and great apes possess a receptor on their cells that detects metabolites from bacteria commonly found in fermented foods and triggers movement of immune cells. Claudia Stäubert of the University of Leipzig and colleagues report these findings in a new study published May 23 in PLOS Genetics.
A new study has shown that restoring environments to include a wider range of species can promote 'good' bacteria over 'bad' -- with potential benefits for human health.
A new study based on a mostly forgotten guide to medicinal plants, 'Resources of the Southern Fields and Forests,' focuses on three of the plants and shows they inhibit bacteria associated with wound infections.