San Diego-Researchers at Rady Children's Institute for Genomic Medicine (RCIGM) have utilized a machine-learning process and clinical natural language processing (CNLP) to diagnose rare genetic diseases in record time. This new method is speeding answers to physicians caring for infants in intensive care and opening the door to increased use of genome sequencing as a first-line diagnostic test for babies with cryptic conditions.
When you eat something super tasty, ever wonder why you really don't want to stop even though you know you've eaten enough? Scientists at the UNC School of Medicine may have found the reason. In lab experiments, UNC's Thomas Kash and colleagues discovered a specific network of cellular communication emanating from the emotion-processing region of the brain, motivating mice to keep eating tasty food even though their basic energy needs had been met.
Teaching big data to future scientists means having them think creatively about ways to harness the terabytes of information available to them. To that end, systems biologist Trey Ideker used his UC San Diego School of Medicine's Biological Networks and Biomedicine graduate course to host a classroom competition tasking students with detecting genes associated with schizophrenia. The winning technique was quick, flexible, and outperformed previously published methods. The details appear April 24 in the journal Cell Systems.
The cells of most life forms contain mitochondria for energy production. They normally have their own genetic material, in addition to that found in the nucleus. Uwe John and colleagues at the Alfred Wegener Institute have now identified the first-ever exception to this rule in a single-celled parasite. The mitochondria of the dinoflagellate Amoebophrya ceratii appear to produce energy just like our own mitochondria, but without any genetic material, as the team reports in the journal Science Advances.
A subset of the stem cells in hair follicles have the potential to regenerate the coating that insulates neurons in mice, reports Thomas Hornyak of the VA Maryland Health Care System and the University of Maryland School of Medicine and colleagues, in a new study published 24th April in PLOS Genetics. The study offers a new direction for finding therapeutic options for certain neurodegenerative diseases.
For scores of wild bee species, females and males visit very different flowers for food -- a discovery that could be important for conservation efforts, according to Rutgers-led research. Indeed, the diets of female and male bees of the same species could be as different as the diets of different bee species, according to a study in the journal PLOS ONE.
Ancient fire remains provide evidence of Neanderthal group mobility and settlement patterns and indicate specific occupation episodes, according to a new study published in PLOS ONE on April 24, 2019, by Lucia Leierer and colleagues from Universidad de La Laguna, Spain.
Densities of endangered green turtles are increasing in Pacific coral reefs, according to the first comprehensive in-water survey of turtle populations in the Pacific. The study, by Sarah Becker of the Monterey Bay Aquarium in California and colleagues, publishes April 24 in the open-access journal PLOS ONE.
Ammonia -- a colorless gas essential for things like fertilizer -- can be made by a new process which is far cleaner, easier and cheaper than the current leading method. UTokyo researchers use readily available lab equipment, recyclable chemicals and a minimum of energy to produce ammonia. Their Samarium-Water Ammonia Production (SWAP) process promises to scale down ammonia production and improve access to ammonia fertilizer to farmers everywhere.
In-soil placement of phosphorus can decrease phosphorus loss in snowmelt runoff