Opioid use disorder treatment during the early months of the COVID-19 pandemic, including medication fills, outpatient visits and urine tests among privately insured individuals, was compared with 2019 in this study.
The results of a pre-clinical study led by researchers at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest how a compound derived from the thunder god vine -- an herb used in China for centuries to treat joint pain, swelling and fever -- is able to kill cancer cells and potentially improve clinical outcomes for patients with pancreatic cancer.
Johns Hopkins Kimmel Cancer Center and Bloomberg~Kimmel Institute for Cancer Immunotherapy researchers identified a correlation between multisystem immune-related adverse events and improved rates of survival. This new information will be helpful in discussing with patients the spectrum of immune side effects that may occur from immunotherapy and the implications for their future.
Researchers from the U.S. Department of Energy's Berkeley Lab and Los Alamos National Laboratory have developed new methods for the large-scale production, purification, and use of the radioisotope cerium-134, which could serve as a PET imaging radiotracer for a highly targeted cancer treatment known as alpha-particle therapy.
Following a stroke, the immune system triggers an inflammatory reaction that can either overshoot or turn into an immune deficiency. Now, a team of researchers - among them scientists from Goethe University Frankfurt, Germany - has shown that tRNA fragments play a role in this immune reaction. Fragments of tRNAs, which transport amino acids during protein synthesis ('transfer RNA'), were long merely considered cellular waste. The researcher's aim: To find new target structures for therapeutics.
In a new study, researchers at Uppsala University have been able to show differences in how Rituximab, a monoclonal antibody drug, interacts with the blood of healthy individuals compared to patients with chronic lymphocytic leukaemia. This has awakened hopes that this analysis method could pave the way for important breakthroughs in immunotherapy research and treatment.
Ever see long lines at the pharmacy counter and give up on a medication, or find that the drive is just a little too long? A study by the University of California, Irvine and UC San Diego found that patients using an automated kiosk in their workplace had better prescription pickup rates without sacrificing instruction from pharmacists.
Researchers from the National University of Singapore have utilised a ground-breaking AI platform to find an optimal combination of available therapies against COVID-19. The research team identified the drug combination from over 530,000 possibilities within two weeks, cutting down the number of tests typically needed by hundreds of thousands.
Doctors may be able to use the findings to identify people at high risk of coronary artery disease and to develop better treatments and preventative interventions.
Mail-order prescriptions shipped in standard bubble-padded envelopes during winter and summer months are likely to spend a substantial portion of time outside the recommended safe temperature range for most medications, according to research presented at the American Society for Health-System Pharmacists (ASHP) Midyear Clinical Meeting and Exhibition.