The more cannabidiol (CBD) in a strain of cannabis, the lower the impairment to brain function, finds a new UCL-led brain imaging study.
The use of thiazide diuretics was associated with a decreased risk of low energy fractures in people with Alzheimer's disease, a new study from the University of Eastern Finland shows. The association was found in long-term use exceeding three years; however, shorter term use did not reduce the risk of fractures. Thiazides are typically prescribed to treat hypertension.
Japanese scientists at Tokyo University of Agriculture and Technology and Yokohama National University have identified the molecular mechanism that gives the skin secretions of a species of frog effective antimicrobial properties. Unravelling the molecular mechanism that facilitates antimicrobial activity of these peptides can help us better understand how the defense system of the frog has evolved, and how this can be used to fight microbial infections of medical importance.
In multiple myeloma, Ig lambda translocations may indicate poor outcomes and resistance to immunomodulatory drugs such as lenalidomide.
Many people fighting a very aggressive form of acute myeloid leukemia (AML) don't survive more than five years. These very sick patients are often unable to receive the only cure -- a bone marrow transplant. Now, an international team of scientists report in Nature Cell Biology on a long-overlooked part of a leukemic cell's internal machinery, where they may have found a key to treating the aggressive blood cancer.
How pharmacy closures are associated with declines in cardiovascular medication adherence for statins, β-blockers and oral anticoagulants among adults 50 or older was the focus of this analysis of prescription claims.
Extracts from the seeds of the Ginkgo biloba tree show antibacterial activity on pathogens that can cause skin infections such as acne, psoriasis, dermatitis and eczema.
EPFL chemists have developed a new, light-based method for modifying peptides at the C-terminal position. The method introduces the structural diversity needed for drug design in this class of bioactive compounds.
A new study shows that a synthetic molecule developed by Oregon Health & Science University scientists stimulates repair of the protective sheath that covers nerve cells in the brain and spinal cord. The study demonstrates in mice that a synthetic molecule called sobetirome efficiently repairs damaged myelin without side effects.
A prescribed drug to treat high blood pressure has shown promise against conditions such as Parkinson's, Huntington's and forms of dementia in studies carried out in mice and zebrafish at the University of Cambridge.