High-throughput analysis of blood plasma could aid in identification of diagnostic and prognostic biomarkers for amyotrophic lateral sclerosis (ALS). The work sheds further light on a pathway involved in disease progression and appears to rule out an environmental neurotoxin as playing a role in ALS.
The Norwegian Directorate for Health and Human Affairs generally recommends more physical activity and less sitting time. But that isn't the right approach to managing neck and back pain for everyone, according to research from the Norwegian University of Science and Technology.
A new study finds the use of HGH treatment in patients that have undergone ACL reconstructive surgery may prevent the loss of muscle strength and weakness.
Dairy products provide more bone-beneficial nutrients than any other food group. Yet a new study based on data from the Study of Women's Health Across the Nation (SWAN) shows that during the menopause transition, when bone loss is accelerated, they offer little benefit in preventing bone mineral density loss or fractures. Study results are published online in Menopause, the journal of The North American Menopause Society (NAMS).
Comparing the postoperative period following the first and second TKA, there were no significant differences in Wong-Baker FACES pain assessment score (WBS) 24, 48, and 72 hrs postoperatively.
An international team of scientists, led by University of Helsinki reported that vitamin B3, niacin, has therapeutic effect in progressive muscle disease. Niacin delayed disease progression in patients with mitochondrial myopathy, a progressive disease with no previous curative treatments.
In a new study in mice, neuroscientists from the University of Copenhagen have found neurons in the brain that control how the mice turn right and left. They hope that the new knowledge can be used in connection with motor disorders in humans.
In a study published today in the journal Proceedings of the National Academies of Science, researchers led by Ara Nazarian, PhD, a principal investigator in the Center for Advanced Orthopaedic Studies at BIDMC, investigated the musculoskeletal phenotype of the homozygous G608G BAC-transgenic progeria mouse model, developed at Dr. Collins' lab at the National Institutes of Health, and determined the phenotypic changes of these mice after a five-arm preclinical trial of different treatment combinations with lonafarnib, pravastatin, and zoledronic acid.
Researchers at Washington University School of Medicine in St. Louis found that gene therapy in mice helped build strength and significant muscle mass quickly, while reducing the severity of osteoarthritis. The gene therapy also prevented obesity, even when the mice were fed a high-fat diet.
A new study published in the Journal of Bone and Mineral Research found that organic nitrates do not have clinically relevant effects on bone mineral density or bone turnover in postmenopausal women, and the medications caused significant side effects.