Researchers have identified the driving force behind a cellular process linked to neurodegenerative disorders such as Parkinson's and motor neurone disease.
A novel method that looks at the molecular composition of brain synapses has revealed three times more proteins than previously thought, finds research published in PNAS.
Pathological changes related to the disability of Parkinson's patients can already be detected in signals from the scalp without the need to open the skull. Researchers from Leipzig University Hospital and the Max Planck Institute for Human Cognitive and Brain Sciences recently published these new findings in the journal Brain.
Scientists have produced a tomato enriched in the Parkinson's disease drug L-DOPA in what could become a new, affordable source of one of the world's essential medicines.
A new study on Alzheimer's disease by Scripps Research scientists has revealed a previously unknown biochemical cascade in the brain that leads to the destruction of synapses, the connections between nerve cells that are responsible for memory and cognition.
According to an article in ARRS' American Journal of Roentgenology (AJR), a prototype 16-channel head Adaptive Image Receive (AIR) radiofrequency coil from GE Healthcare outperformed a conventional 8-channel head coil for in vivo whole-brain imaging, though it did not perform as well as a conventional 32-channel head coil.
Jessica Huber, a professor of Speech, Language, and Hearing Sciences and associate dean for research in Purdue's College of Health and Human Sciences, leads Purdue's Motor Speech Lab. Huber and her team are now doing virtual studies to evaluate speech disorders related to Parkinson's using artificial intelligence technology platforms.
Rice University biochemists have proposed that degenerative diseases as varied as Alzheimer's, Parkinson's and muscle atrophy occur in two distinct phases marked by protein signaling changes that could result in patients responding differently to the same treatment.
A simple eye exam combined with powerful artificial intelligence (AI) machine learning technology could provide early detection of Parkinson's disease, according to research being presented at the annual meeting of the Radiological Society of North America (RSNA).
Though neurodegenerative diseases are becoming more common in today's aging societies, the exact way in which accumulated abnormal proteins become toxic to neurons is unknown. In a recent study conducted at Daegu Gyeongbuk Institute of Science and Technology, Korea, scientists have discovered a new mechanism of action by which these abnormal proteins actually unlock the normally latent toxicity of native proteins. Their results represent a completely new avenue toward the development of effective therapies.