A new study links air pollution to changes in the human gut microbiome which could fuel diabetes, obesity and inflammatory bowel diseases like colitis and Crohn's disease.
Life expectancy is influenced not only by the traditional lifestyle-related risk factors but also by factors related to a person's quality of life, such as heavy stress.
The blood test method makes use of machine learning and can be used to predict whether patients will put on weight, unless they change their habits. The project was conducted in Brazil with funding from FAPESP.
MIT researchers have developed a mathematical model that can predict the behavior of glucose-responsive insulin in humans and in rodents. They believe this model could be used to design GRIs that are more likely to work in patients with diabetes.
Bacteria may be involved in the development of type 2 diabetes, according to a study published today in Nature Metabolism by researchers from Université Laval, the Québec Heart and Lung Institute (IUCPQ), and McMaster University. The authors found that the blood, liver, and certain abdominal fat deposits in diabetics have a different bacterial signature than in non-diabetics.
Findings in this observational study of almost 387,000 children born in the US don't show evidence of an association between rotavirus vaccination (routinely recommended for all infants by age 8 months) and type 1 diabetes in children who were followed over a range of about 5 years. Researchers explain limitations of the study, as well as two potential unmeasured confounding variables that may have affected results.
Dental professionals could play a vital role in the diagnosis of Type 2 diabetes as well as identifying those at a high risk of developing the condition, new research by a team at the University of Birmingham's School of Dentistry has found.
The PCORnet Bariatric Study provides real-world evidence from analyses of tens of thousands of patient records that helps people considering weight-loss surgery to weigh the tradeoffs of the two main surgical procedures and make personalized decisions on which is best for them. The study findings are now being incorporated in a decision aid to power shared decision-making between patients and clinicians.
Researchers at Western University are studying a molecule found in sweet oranges and tangerines called nobiletin, which they have shown to drastically reduce obesity and reverse its negative side-effects. But why it works remains a mystery.
Chronic kidney disease (CKD) affects hundreds of millions of people worldwide and is linked to salt-sensitive hypertension. Researchers from Tokyo Medical and Dental University have now found that pro-inflammatory cytokine TNF-α triggers salt-sensitive hypertension in CKD patients via the WNK-SPAK-NCC pathway by inhibiting transcription of NEDD4-2, an E3 ligase that regulates WNK1 protein abundance. Understanding this mechanism provides new targets for future salt-sensitive hypertension therapies.