Whether a higher or lower dose of the muscle relaxant baclofen was associated with 30-day risk of hospitalization with encephalopathy (defined as a main diagnosis of delirium, disorientation, transient alteration of awareness, transient ischemic attack or an unclear diagnosis of dementia) among newly prescribed patients with chronic kidney disease was the focus of this observational study with nearly 16,000 older adults.
Data from about 5 million people (with and without diabetes) in 28 countries were used to develop equations to help identify people at increased five-year risk of chronic kidney disease, defined as reduced estimated glomerular filtration rate (eGFR).
Researchers in this randomized clinical trial investigated if supplementation with vitamin D or omega-3 fatty acids compared with placebo over five years helped prevent the development or progression of chronic kidney disease among adults with type 2 diabetes. The main outcome measure was change in the glomerular filtration rate that was estimated from serum creatinine and cystatin C.
A plane has to be going pretty fast for a mere raindrop to crack its windshield, but it can happen. While scientists knew surface waves were behind the phenomenon, the details have long remained fuzzy. But thanks to new models of the physics behind the improbable feat, it may just help doctors crack kidney stones to pieces.
Using US transplant registry data, clinical researchers at the University of Pittsburgh found that kidney transplants between identical twins have high success rates, but also surprisingly high rates of immunosuppressant use.
USC researchers have completed a detailed deconstruction of the kidney, revealing for the first time an intimate portrait of gender differences and more in the organ.
Men with higher levels of 'free' testosterone and a growth hormone in their blood are more likely to be diagnosed with prostate cancer, according to research presented at the 2019 NCRI Cancer Conference.
New research shows that antibiotic-resistant E.coli superbugs are spread through poor toilet hygiene, not undercooked chicken or other food. Scientists sequenced the genomes of resistant E. coli from sources including human bloodstream infections, faeces and sewerage, animal slurry and meat including beef, pork, chicken, fruit and salad. While we must carry on cooking chicken well and never alternately handle raw meat and salad, in the case of ESBL-E.coli -- it's more important to wash hands after going to the toilet.
* Bladder cancer research has been hampered by the inability to establish stable long-term cultures of normal urothelial cells, responsible for 90% of these tumours * CNIO researchers used organoid technology to establish long-term cultures that maintain their identity, from which they identified a population of proliferating stem cells that could not be studied until now * The results of this work may usher in a new era in the study of urinary system diseases and tissue regeneration
Nearly 50% of menopausal women complain of vaginal dryness, itching, and burning, among other commonly reported menopause symptoms. Laser therapy is one of the newer techniques for addressing these problems. A new study suggests that it is as effective and safe as vaginal estrogen in improving sexual and urinary functionality. Results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).