Melbourne researchers have identified a microscopic 'ingredient' that can be added to a malaria vaccine for efficient protection against the deadly pathogen.
Researchers at Baylor College of Medicine and colleagues identify critical points to pay close attention to when designing and developing COVID-19 vaccines.
These new drugs are capable of blocking the growth of hepatic and renal cysts in experimental models of polycystic hepatorenal disease. After receiveing the FIPSE national award for Innovation, the drugs were patented and licensed to a pharmaceutical company in the Basque Country for the purpose of furthering their clinical study.
France and the United States have experienced a tremendous reduction in the number of organ donations and solid organ (kidney, liver, heart, and lung) transplant procedures since the onset of the COVID-19 pandemic. By early April, transplant centers in both countries were conducting far fewer deceased donor transplants compared to just one month earlier, with the number of procedures dropping by 91% in France and 50% in the United States.
In a new special issue of Clinical Gastroenterology and Hepatology, the clinical practice journal of the American Gastroenterological Association (AGA), leading international experts provide a comprehensive update on the treatment of inflammatory bowel diseases (IBD) for the practicing clinician
AGA has published new expert recommendations in Gastroenterology: AGA Institute Rapid Review of the GI and Liver Manifestations of COVID-19, Meta-Analysis of International Data, and Recommendations for the Consultative Management of Patients with COVID-19.
Before and after the introduction of lifesaving drugs for hepatitis C, researchers found that from 1979 to 1998, racial inequalities in mortality from liver cancer in the US were declining. But, from 1998 to 2016, of the 16,770 deaths from liver cancer among blacks, the excess relative to whites increased from 27.8 percent to 45.4 percent. Concurrently, racial inequalities in death decreased for major risk factors for liver cancer, such as alcohol, obesity and diabetes.
Toxin exposure appears to have contributed to dramatically higher rates of fatty liver disease among first responders to the attack on the World Trade Center on Sept. 11, 2001, according to research that was selected for presentation at Digestive Disease Week® (DDW) 2020. DDW® data will be published in the May online supplements to Gastroenterology and GIE: Gastrointestinal Endoscopy.
This study shows that the molecular regulatory mechanism of TGF-β-induced downregulation of CYGB expression in human HSCs, leading to the loss of cellular tolerance to exogenous oxidative stress and oxidative DNA damage in activated HSCs in human NASH with advanced fibrosis. Our findings provide new insights into the relationship between CYGB expression and the pathophysiology of NASH fibrosis in the human liver.
Death rates from prostate cancer are predicted to fall in 2020 in the EU, largely due to better diagnosis and treatment, according to new research published in the leading cancer journal Annals of Oncology. Death rates from lung and pancreatic cancers continue to rise in women. A total of 1.4 million people are predicted to die from all cancers by the end of 2020.