Researchers may have found a group of immune cells that increase in number with age but are too worn out to fight diseases. The accumulation of dysfunctional virtual memory T cells, in addition to the loss of true naïve T cells, may explain why older people have reduced immune responses to cancer and vaccines, why cancer immunotherapy is less successful in the elderly, and may help to tailor cancer immunotherapy treatments specifically for older patients.
Scientists have identified the key response that children use to control infections.
Glial cells surround neurons and provide support -- not unlike hospital staff and nurses supporting doctors to keep operations running smoothly. These often-overlooked cells, which include oligodendrocytes and astrocytes, are the most abundant cell types in the central nervous system. But these cells do more than support neurons. They also actively influence them, University of California, Riverside, researchers report.
An algorithm to monitor the joints of patients with arthritis, which could change the way that the severity of the condition is assessed, has been developed by a team of engineers, physicians and radiologists led by the University of Cambridge.
Ancient Greek philosopher Aristotle observed that larger animals tend to live longer than smaller ones. On June 18 in the journal Developmental Cell, scientists report that it's cell size, not body size, that intrinsically correlates with and perhaps affects lifespan. By examining the pancreases of 24 mammalian species -- including shrews, humans, and tigers -- researchers found that animals with larger pancreatic cells tend to age faster, while smaller cells seem to go hand in hand with longer lifespans.
A new study from the Keck School of Medicine of USC shows that African-Americans and Latinos who are diagnosed with diabetes after age 50 have a more than threefold risk of developing pancreatic cancer.
Lihong Wang, Caltech's Bren Professor of Medical Engineering and Electrical Engineering, has developed a laser-sonic scanning system that can identify breast tumors quickly and safely.
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) suggest that gout is associated with a 17-20 percent higher risk of dementia in the elderly.
Could being more knowledgeable about finances help to keep you out of the hospital? Older adults with higher financial literacy are at lower risk of being hospitalized, reports a study in the July issue of Medical Care. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Newly published research provides important evidence supporting the long-term safety and viability of bariatric surgery. The study finds that muscle mass and fat-free mass (organs, bones, tissues) levels are maintained in the body following a rapid post-surgical weight loss. The finding dispels fears that gastric bypass surgery may result in a detrimental loss of muscle that continues for years after initial weight loss, leading to long-term muscle insufficiency despite weight regain.