Generative biology meets generative chemistry: bidirectional conditional autoencoder to generate novel molecular structures for the desired transcriptional response.
More than 100,000 Norwegians have atrial fibrillation. They should be actively exercising for their health.
Characterized by a buildup of amyloid plaques in the brain, Alzheimer's is an irreversible disease that leads to memory loss and a decrease in cognitive function. More than 5 million Americans suffer with the brain condition, which is the sixth leading cause of death in the United States. While the causes of Alzheimer's are not fully understood, scientists believe genetic, lifestyle and environmental factors are involved in the disease's development.
Solving problems, planning one's own actions, controlling emotions -- these executive functions are fundamental processes for controlling our behavior. Despite numerous indications, there has not yet been any clear evidence to support which brain areas process these abilities. A study at the Max Planck Institute for Human Cognitive and Brain Sciences (MPI CBS) has now succeeded in identifying the crucial region -- with the help of a unique patient and the not-so-rare dysexecutive syndrome.
New research has found that older adults who go online every day are more likely to be socially isolated than those who use the internet less frequently.
Some of LA's most disadvantaged communities are vulnerable to extreme heat waves, which are increasingly common due to global warming.
MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions. HDAC1 is often diminished in both Alzheimer's patients and in normally aging adults, and the study suggests restoring it could have positive benefits for both groups.
Older age, being male, deprivation, living in a densely populated area, ethnicity, obesity, and chronic kidney disease are associated with a positive test for COVID-19, according to results from 3,802 people tested for SARS-CoV-2 (including 587 positive tests) in the UK. The observational study was conducted in between Jan 28 and April 4 using routine electronic health records data from GP practices across England (UK), and results are published in The Lancet Infectious Diseases journal.
Biomedical engineers at Duke University have devised a new imaging device capable of measuring both the thickness and texture of the various layers of the retina. The advance could be used to detect a biomarker of Alzheimer's disease, potentially offering a widespread early warning system for the disease.
Scientists have devised a mouse model that lets researchers track every cell in the body, from the embryonic stage until adulthood. Using a "barcoding" technique and CRISPR gene editing technology, the model can identify different cell types as they emerge and what genes each is turning on. The model offers a way to reconstruct every single cell lineage, cell-by-cell, as an embryo develops, or as a tissue is built up.