Close to one in two cases of dementia could be preventable in low- to middle-income countries, finds a new UCL study. The findings, published in The Lancet Global Health, found how improving childhood education and other health outcomes throughout life could reduce the risk of dementia.
Low scam awareness in older people is associated with risk for developing Alzheimer dementia or mild cognitive impairment in the future. These findings suggest that changes in social judgment occur before changes in thinking or memory are recognizable. Findings from a prospective cohort study are published in Annals of Internal Medicine.
For decades, hospitals have worked to get staff to wash their hands and prevent the spread of germs. But a new study suggests they may want to expand those efforts to their patients, too. Fourteen percent of 399 hospital patients had 'superbug' antibiotic-resistant bacteria on their hands or nostrils early in their hospital stay, and nearly a third of tests for such bacteria on objects that patients commonly touch came back positive.
Treatment with a choline kinase inhibitor prompts immune cells to clear away damaged mitochondria, thus reducing NLRP3 inflammasome activation and preventing inflammation.
An international team of scientists has mapped a molecular complex that could aid in the development of better medications with fewer side effects for osteoporosis and cancer. The near-atomic resolution images depict parathyroid hormone receptor-1 (PTH1R), a molecule that conveys signals to and from cells, interacting with two key messengers -- a molecule that mimics parathyroid hormone, one of the most important regulators of calcium levels in the body, and a stimulatory G protein, a molecule that mediates bone turnover.
Income and social status have an increasing effect on life expectancy in Germany. On average, men with very low retirement pay die five years earlier than those who are much better off. Poverty shortens life.
Chronic diseases are a key factor limiting the mobility of older people. Usually individuals are conscious of their condition in the case of an acute musculoskeletal disorder that causes pain or functional limitations. However, if the condition has progressed slowly, the gradual restriction of mobility often goes unnoticed.
USC researchers and collaborators report a breakthrough to prevent osteonecrosis of the jaw, a side effect suffered by some people undergoing treatment for cancer or osteoporosis.
Colorado State University Professor Susan Bailey, who studies telomeres, or the protective 'caps' on the ends of chromosomes, found that Scott Kelly's telomeres in his white blood cells got longer while in space. Changes in telomere length could mean a person is at risk for accelerated aging or the diseases that come along with getting older.
Researchers at the Center for BrainHealth®, part of The University of Texas at Dallas, combined two non-pharmacological interventions for adults with Mild Cognitive Impairment (MCI): eight sessions of Strategic Memory Advanced Reasoning Training (SMART), a cognitive training program shown to improve reasoning and ability to extract bottom-line messages from complex information; and Transcranial Direct Current Stimulation (tDCS) over the left frontal region, associated with cognitive control and memory recovery success in people with Alzheimer's.