Elevated blood levels of toxic chemicals found in pesticides, nonstick cookware, and fire retardants have been tied to an increased risk for celiac disease in young people, new research shows.
Funding partners JDRF, the American Diabetes Association (ADA), and The Leona M. and Harry B. Helmsley Charitable Trust, in partnership with the University of Florida, announce the results of a study examining the consistency and potency of insulin purchased at U.S. retail pharmacies.
New study identifies that differences in insulin resistance can explain in part the disparities in breast cancer survival between black and white women.
Researchers from Kubicek's and Bock's groups at CeMM have developed a method to accurately assess the effect of specific drugs in isolated pancreatic tissue by using a refined single-cell RNA sequencing method. Their Genome Biology publication describes their technique to overcome the problem of contaminating RNA molecules in single-cell transcriptomics, allowing for accurate results of dynamic drug responses in pancreatic cells. These findings will support the development of targeted drug therapies for treationg T1 diabetes.
Millions of people around the world use acid suppressants called proton pump inhibitors for conditions like heartburn, gastritis and stomach ulcers. Researchers at Karolinska Institutet in Sweden now report that how the long-term use of these drugs could increase the risk of developing dementia. Their results are published in the journal Alzheimer's & Dementia.
A scientific team found a new metabolism regulation system for the brown adipose tissue using the kallikrein-kinin hormonal system, so far related to the physiology of the renal and cardiovascular system and inflammation and pain processes. This molecular auto-control system of lipidic metabolism, so far unknown, could help prevent the damaging effects derived from an excessive activation of the brown adipose tissue.
A study of 4,532 men in the Veneto region of Italy has found that those who were being treated for prostate cancer with androgen-deprivation therapies (ADT) were less likely to develop the coronavirus COVID-19 and, if they were infected, the disease was less severe. The study is published in Annals of Oncology.
This research, published in Nature, shows how different populations of people share most of the genetic susceptibilities to developing type 2 diabetes but do have some different genetic variations that can make them more or less susceptible to developing the condition.
In the largest study of its kind in any non-European population, an international team of researchers, including a University of Massachusetts Amherst genetic epidemiologist, has identified new genetic links with type 2 diabetes among 433,540 East Asian individuals.
Black males start puberty at younger ages than males of other racial or ethnic groups, and early puberty has been linked to risks for negative outcomes, yet we know little about how black males navigate the changes in their bodies or understand their social identities. A new study explored how young African-American and Caribbean black males understand these matters and how variations in their understanding affect their self-concept and well-being.