Nonalcoholic fatty liver disease, or NAFLD, which affects roughly 100 million Americans, costs the United States healthcare system $32 billion annually, according to a first-of-its-kind study by Intermountain Healthcare researchers on the economic impact of the disease.
Researchers examine testosterone's effect on men's desire for goods that are considered to have social cachet.
In pigs, endocrine disruptors can alter gene expression in a way that also affects the next generation. This has been shown by a team of researchers from ETH Zurich and the Technical University of Munich. The study findings could potentially apply to humans, too.
The Endocrine Society today issued a Clinical Practice Guideline advising healthcare providers on how to diagnose and treat the endocrine disorders that affect a significant portion of childhood cancer survivors in the United States today.
More than 5,000 physicians, technologists, scientists and exhibitors gathered for the Society of Nuclear Medicine and Molecular Imaging's 65th Annual Meeting, held June 23-26 in Philadelphia. With nuclear medicine playing a growing role in providing precision medicine, theranostics (combining diagnostic imaging and targeted radionuclide therapy) were an important focus throughout the meeting.
In this review, the complexity of immune-suppressive mechanisms in the tumor milieu of cancers, including oral malignancy is discussed in relation to immune check point inhibitors, regulatory T cells (Treg), myeloid-derived suppressor cells (MDSCs) and cancer associated fibroblasts (CAFs).
A new form of immunotherapy reactivates the response to hormone treatment in advanced prostate cancer, a study in mice and human tissue has found. Hormone therapy is a mainstay of prostate cancer treatment - but tumour cells can grow resistant, leading to a hard-to-treat, advanced form of the disease. The new study found that blocking a protein produced by a type of immune cell - known as granulocytic myeloid-derived suppressor cells - restored sensitivity to hormone therapy.
Patients with Type 2 diabetes who were treated with the newer generation of insulin analog drugs did not have substantially better outcomes than those treated with less costly human insulin, according to a study by Yale School of Medicine researchers and colleagues at Kaiser Permanente. The study is published in the June 23 issue of Journal of the American Medical Association.
New research from the University of Pittsburgh School of Medicine shows that white bloods cells, which typically heal infections and injuries, can become overactive and cause inflammation in plaques in blood vessels, making them vulnerable to rupture and hemorrhage in people with diabetes.
Medicines used to treat diabetes in adults are not as effective in slowing the progression of the disease in youth, a major, multi-institutional study now shows. The findings are disturbing because type 2 diabetes among youth is a growing problem. The researchers point to the need to develop new approaches to treat adolescents with the disease.