Antidepressant use in people with chronic obstructive pulmonary disease (COPD) is associated with a 20 percent increase in likelihood of death and a 15 percent increase in likelihood of hospitalization due to related symptoms, finds a new study led by researchers at St. Michael's Hospital.
Ataxin-2 is an essential protein of the nervous system. Authors of the study focus on a particular domain of Ataxin-2 known as the intrinsically disordered region (IDR) which was hitherto largely unknown. he study would have important bearings into the diverse scenarios disrupting normal brain functions.
A multinational collaboration of researchers found that efavirenz, the key component of the most commonly used HIV cocktail in the world, was not associated with increased risk for depression or suicide in patients living with HIV in Uganda. These findings conflict with previous reports from the United States and Europe linking efavirenz with adverse psychiatric side effects. The study is published in Annals of Internal Medicine.
A new CAMH and Institute for Clinical Evaluative Sciences study shows that people with schizophrenia account for more than one in 10 cases of suicide in Ontario, and that young people are disproportionately affected. People with schizophrenia also had more contact with the health care system, pointing to an opportunity to intervene. The researchers emphasize the need for early suicide risk assessments to reduce risks.
The risk of mortality, and of developing a number of cancers, is lowest in light drinkers consuming an average of less than one drink per day across their lifetime, and the risk of some cancers increases with each additional drink per week, according to a new study, published this week in PLOS Medicine by Andrew Kunzmann of Queen's University Belfast, and colleagues.
The average 10-year risk of developing cardiovascular disease varies widely among India's states, ranging from 13.2 percent to 19.5 percent, with substantial variation across socio-demographic groups according to a study published this week in PLOS Medicine by Pascal Geldsetzer and Rifat Atun of Harvard University, and colleagues.
A combination of elevated fasting glucose and HbA1c levels from a single blood sample was found to be accurate for diagnosing diabetes. This is significant because current guidelines state that a second blood test, conducted a separate point in time, is requited to confirm a diagnosis of diabetes. Findings from a prospective cohort study are published in Annals of Internal Medicine.
The results of a 23-year, follow-up study presented today at the Annual European Congress of Rheumatology (EULAR 2018) suggest early, intensive treatment of rheumatoid arthritis has long-term benefits including the normalization of mortality to levels consistent with the general population.
More than 500,000 years of life expectancy were lost in Ohio during a seven-year period, according to a study conducted by The Ohio Alliance for Innovation in Population Health (OAIPH) -- a collaborative initiative formed by Ohio University's College of Health Sciences and Professions and the University of Toledo's College of Health and Human Services.
Researchers from the University of Ottawa sought to compare the prognostic accuracy of the Sepsis-3 septic shock criteria with the SIRS-based septic shock criteria for prediction of in-hospital mortality among patients hospitalized with suspected infection, receiving a RRT assessment for acute deterioration.