In new studies conducted at UC San Francisco, a novel oxygen-delivery therapeutic restored the function of oxygen-starved heart tissue in an animal model of global hypoxia. Unlike its experimental predecessors, the new drug does not appear to cause systemic side effects or overcorrect with excessive blood oxygenation, which can itself be toxic. Instead, the new drug delivers its precious oxygen cargo only to the tissues that need it most.
Since 2013, gifts and payments to doctors by pharmaceutical and medical device companies have been publicly reported. Some medical centers, employers, and states have banned or restricted detailing visits, physician payments or gifts. In order to better understand the effects of these changes, a team of researchers from Harvard Medical School, The Dartmouth Institute for Health Policy and Clinical Practice, and the American Board of Internal Medicine conducted a national survey of internal medicine doctors.
A five-year study of hospital statistics from the United States shows that the incidence of stroke has risen steadily among marijuana users even though the overall rate of stroke remained constant over the same period.
Research shows metformin, a commonly prescribed drug for type 2 diabetes prevents heart disease in patients with type 1 diabetes.
Researchers recently designed a study to explore whether physical activity could lower the high rate of death associated with frailty in older people. Their study was published in the Journal of the American Geriatrics Society.
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A new study led by CNIC researcher Andrés Hidalgo and published in the Journal of Experimental Medicine shows that in addition to its defense function and the associated damage to affected tissues, the immune system also plays an important role in the day-to-day function of healthy organs. The research results show that the immune cells called neutrophils help to maintain the normal function of healthy tissues
A surgical technique called EDAS (encephaloduroarteriosynangiosis) significantly decreases the rate of stroke recurrence and death for patients with severe atherosclerosis of the brain arteries, according to findings of a Phase IIa clinical trial presented today at the World Stroke Congress in Montreal.
Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered a new inflammation control mechanism that shows how the damage caused by the immune response can be controlled.
The potent combination of CRISPR/Cas9 and zebrafish as a model organism offers enormous potential for research into human diseases caused by point mutations. Three new articles published in Disease Models & Mechanisms use zebrafish to explore how advances in CRISPR/Cas9 optimisation offer a new level of accuracy and specificity previously out of reach for research into this type of human genetic disorder.