Dendritic cells patrol the body for invaders and activate T cells and natural killer cells to attack them, making them crucial players in keeping cancer and other diseases at bay. A new biomaterial-based technique now allows dendritic cells to be tagged, tracked, and controlled within the body for the first time. When deployed in mice, this system both treated and prevented lung cancer tumors, and shows promise for other immune conditions as well.
- Nature Materials
- National Institutes of Health, Wyss Institute for Biologically Inspired Engineering, National Science Foundation, Canadian Institutes of Health Research