Increased mortality associated with nocturia

LINTHICUM, MD, April 26, 2009–Patients suffering from nocturia, the need to urinate at least twice during the night, may have a significantly increased risk for mortality. Researchers presented a study at the 104th Annual Scientific Meeting of the American Urological Association (AUA) showing that there was a significantly increased mortality rate in elderly patients living in a Japanese assisted-living facility who suffered from nocturia relative to other residents.

Researchers conducted a comprehensive geriatric assessment of 788 residents 70 years old or older to determine incidence of nocturia. Using data from a national health insurance system, researchers assessed differences in survival stratified by presence or absence of nocturia over three years. Researchers adjusted the models to control for age, sex, BMI, diabetes, hypertension, history of coronary heart disease, nephropathy, alcohol consumption, and use of tranquilizers, hypnotics or diuretics.

"Nighttime urination is not necessarily just a matter of getting older. Patients should talk to their doctor about what may be causing this," said Anthony Y. Smith, MD, an AUA spokesman. "There may be a very serious yet treatable condition involved."

NOTE TO REPORTERS: Experts are available to discuss this study outside normal briefing times. To arrange an interview with an expert, please contact the AUA Communications Office at the number above or e-mail Lacey Dean at LDean@AUAnet.org.

Nakagawa, H; Niu, K; Hozawa, A; Ikeda, Y; Kaiho, Y; Masuda-Ohmori, K; Nagatomi, R; Tsuji, I; Arai, Y. Association between nocturia and mortality in a community-dwelling elderly population aged 70 years and over: results of a 3-year prospective cohort study in Japan. J Urol, suppl. 2009: 181, 4, abstract 20.

About the American Urological Association: Founded in 1902 and headquartered near Baltimore, Maryland, the American Urological Association is the pre-eminent professional organization for urologists, with more than 16,000 members throughout the world. An educational nonprofit organization, the AUA pursues its mission of fostering the highest standards of urologic care by carrying out a wide variety of programs for members and their patients.